APA Lyme Disease

 Lyme Disease Case Study A 38-year-old male had a 3-week history of fatigue and lethargy with intermittent complaints of headache, fever, chills, myalgia, and arthralgia. According to the history, the patient’s symptoms began shortly after a camping vacation. He recalled a bug bite and rash on his thigh immediately after the trip. The following studies were ordered: Studies Results Lyme disease test, Elevated IgM antibody titers against Borrelia burgdorferi (normal: low) Erythrocyte sedimentation rate (ESR), 30 mm/hour (normal: ≤15 mm/hour) Aspartate aminotransferase (AST), 32 units/L (normal: 8-20 units/L) Hemoglobin (Hgb), 12 g/dL (normal: 14-18 g/dL) Hematocrit (Hct), 36% (normal: 42%-52%) Rheumatoid factor (RF), Negative (normal: negative) Antinuclear antibodies (ANA), Negative (normal: negative) Diagnostic Analysis Based on the patient’s history of camping in the woods and an insect bite and rash on the thigh, Lyme disease was suspected. Early in the course of this disease, testing for specific immunoglobulin (Ig) M antibodies against B. burgdorferi is the most helpful in diagnosing Lyme disease. An elevated ESR, increased AST levels, and mild anemia are frequently seen early in this disease. RF and ANA abnormalities are usually absent. Critical Thinking Questions 1. What is the cardinal sign of Lyme disease? (always on the boards) 2. At what stages of Lyme disease are the IgG and IgM antibodies elevated? 3. Why was the ESR elevated? 4. What is the Therapeutic goal for Lyme Disease and what is the recommended treatmen 

 
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quantitative research paper

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J Nurs Care Qual Vol. 29, No. 4, pp. 318–326 Copyright c© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins

Analysis of Nurse Staffing and Patient Outcomes Using Comprehensive Nurse Staffing Characteristics in Acute Care Nursing Units

Sung-Heui Bae, PhD, MPH, RN; Maureen Kelly, MS, RN; Carol S. Brewer, PhD, RN, FAAN; Alexandra Spencer, MSN, RN

Associations between comprehensive nurse staffing characteristics and patient falls and pressure ulcers were examined using negative binomial regression modeling with hospital- and time-fixed effects. A convenience sample was collected from 35 nursing units in 3 hospitals. Rates of patient falls and injury falls were found to be greater with higher temporary registered nurse staffing levels but decreased with greater levels of licensed practical nursing care hours per patient day. Pressure ulcers were not related to any staffing characteristics. Key words: nurse staffing, patient falls, pressure ulcers, temporary nursing staff, turnover

IT has been predicted that in the UnitedStates, 300 000 to 1 million new regis- tered nurses (RNs) will be needed in 2020.1

Although the current economic recession has seen an increase in RN employment and some

Author Affiliations: School of Nursing, University of Texas at Austin (Dr Bae); Roswell Park Cancer Institute, Buffalo, New York (Ms Kelly); School of Nursing, University at Buffalo, New York (Dr Brewer); and Catholic Health System, Cheektowaga, New York (Ms Spencer).

The John R. Oishei Foundation provided funding for this research.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (www.jncqjournal.com).

The authors declare no conflict of interest.

Correspondence: Sung-Heui Bae, PhD, MPH, RN, Assis- tant Professor, School of Nursing, University of Texas at Austin, 1710 Red River Street, Austin, TX 78701 (sbae@nursing.utexas.edu).

Accepted for Publication: January 20, 2014

Published ahead of print: February 6, 2014

DOI: 10.1097/NCQ.0000000000000057

easing of the nursing shortage, researchers still project renewed post-recession demand and large shortages for the future.2 These shortages are expected to have severe effects on the quality of patient care. Nursing short- ages often lead to suboptimal staffing char- acteristics such as low staffing levels, high turnover, high use of temporary (agency) staff, low RN professional staff mix, and greater use of nurse overtime.3-5 Previous studies have shown that nurse staffing levels and RN skill mix are related to lower quality of patient care.6-9 However, limited empirical research has been conducted to examine the impact of nurse turnover and the use of tem- porary nursing staff on quality of care in com- bination with staffing levels and RN skill mix in acute care hospital settings. Therefore, the purpose of this study was to examine the rela- tionship of nurse staffing to quality of patient care outcomes, by including not only nursing turnover and temporary nursing staff but also nurse staffing levels and RN skill mix.

A major consequence of turnover is the loss and disruption of organizational processes,

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Analysis of Nurse Staffing and Patient Outcomes 319

which can be detrimental to both the effec- tiveness and productivity of care delivery.10,11

High turnover creates an unstable workforce and has a negative impact on workgroup dy- namics. As turnover increases, the remain- ing staff must constantly adjust to new staff; turnover can then affect the interactions and integration within the workgroup,12 resulting in poor workgroup cohesiveness, demoraliza- tion, communication breakdowns, and frag- mented coordination.12-14 Researchers have found that high levels of staff turnover were associated with poor quality of care.15-18

Conversely, however, other researchers have suggested that some turnover might be ben- eficial, improving the quality of patient out- comes as new people and ideas enter the workgroup and keeping the organization from becoming stagnant.19 Employee mobil- ity is also important for innovation because it enables organizations to become more flexi- ble and adaptable to change.20 Innovation can enable a workgroup to learn from errors.15,21

Research findings about the use of tempo- rary staff are also mixed. The main reasons for employing temporary nursing staff include staff absences, recruitment, retention, and vacancies.22 Hiring temporary nursing staff can help to increase staffing levels; however, it can also affect other staff as well as facility operations, thus leading to poorer patient care.23,24 Higher use of temporary staff can increase administrative burdens, disrupt rou- tines and teamwork, and require additional supervision by permanent staff.23 It may also interfere with continuity of care. The use of temporary nurses has been related, for exam- ple, to the spread of nosocomial infections among patients,25 needlestick injuries among temporary nurses,26 and medication errors.27

However, Aiken and colleagues have argued that using temporary nurses may not hinder quality of care because current working schedules do not permit continuity of care (ie, prevalent use of 12-hour shifts for 3 days per week) and found that temporary nursing staff were not less qualified than permanent staff.28,29 Using temporary nursing staff was not related to the quality of patient care, but

other work environment characteristics were related to that.29,30

As stated earlier, there is strong, though mixed, evidence regarding the impact of nurs- ing turnover and the use of temporary nursing staff on the quality of patient care, and there is evidence regarding staffing levels and RN skill mix. However, previous studies on nurse staffing and quality of care have not consid- ered nursing turnover and temporary nurse staffing characteristics together with nurse staffing levels and professional skill mix in acute care hospital settings.

METHODS

Design and sample

The data used in the study were col- lected by the Western New York Center for Workforce and Quality. These data consist of nursing-sensitive quality indicators and nurse staffing data obtained in 75 nursing units at 6 hospitals. Among those 6 hospitals, only 3 hospitals provided data for all variables re- quired for this study. As a result, we only used the subset of 3 hospitals’ data. The subset of the data was collected retrospectively from October 2010 to March 2012 in 35 nursing units at the 3 hospitals.

Data for 4 nurse-staffing characteristics (nurse staffing, skill mix, nursing turnover, and temporary nursing staff) and for 1 pa- tient outcome (patient falls) were collected monthly. Injury falls were collected monthly. However, incidents of injury falls were rare with small variation in monthly data, so we aggregated monthly data of injury falls into quarterly data, which were used for the cur- rent study. For total pressure ulcers and unit- acquired ulcers, only quarterly data were available for the analysis. Thus, quarterly data for these 2 patient outcomes (patient falls with injuries; pressure ulcers, including both total pressure ulcers and unit-acquired pres- sure ulcers) were used (see Supplemental Digital Content, Table, available at http:// links.lww.com/JNCQ/A73). A total of 511 unit-month data points and 171 unit-quarter

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320 JOURNAL OF NURSING CARE QUALITY/OCTOBER–DECEMBER 2014

data points were used for the analytic sample. This study was approved by the institutional review boards of the authors’ universities and the 3 participating hospitals.

Measures

Patient outcome variables

Nursing unit patient falls, patient falls with injuries, and pressure ulcers (both total pres- sure ulcers and unit-acquired pressure ulcers) were used as measures of patient out- comes. These patient outcomes are recog- nized nursing-sensitive quality indicators.31,32

For this study, the operational definitions of each patient outcome variable are the same as those used for the National Database of Nurs- ing Quality Indicators.33 Monthly patient falls and quarterly patient falls with injuries were defined as the number of incident adjusted per 1000 patient days. Quarterly pressure ul- cers (total pressure ulcers and unit-acquired pressure ulcers) were defined as prevalence rates. The Supplemental Digital Content Table (available at http://links.lww.com/JNCQ/ A73) presents definitions for each patient out- come variable.

Nurse staffing variables

To capture the effects of different types of nurse staffing, we used nursing hours per patient day for RNs, licensed practical nurses (LPNs), and unlicensed assistive per- sonnel (UAP). Skill mix indicated the propor- tion of RNs to LPNs and UAPs. For nursing turnover and temporary nursing staff, we used RN turnover rate and temporary RN care hours per patient day, because RNs make up the majority of nursing staff and provide the most critical components of nursing care. After assessing the distribution of RN tempo- rary nursing care hours, we categorized RN temporary nursing care hours into 3 groups by using zero and 0.3 care hour as cutoff points (low, moderate, and high). There are 2 reasons for that. First, more than 60% of the sample had zero care hours, so we cre- ated this as a group (low levels). Second, among those units using temporary nursing staff, we created 2 other groups to distinguish

those units with higher levels of the use of temporary RNs (≥0.3 care hour) from those units with moderate levels (>0 and <0.3 care hour). Detailed information of definitions of the nurse staffing variables is presented in Sup- plemental Digital Content Table (available at http://links.lww.com/JNCQ/A73).

Unit covariates

To control for other nursing unit character- istics that might affect both nurse staffing and patient outcomes, several nursing unit charac- teristics were included as covariates: unit size, unit type (critical care units, step down units, medical/surgical units, and other units), and quality improvement initiatives (transforming care at the bedside units and dedicated ed- ucation units). In addition, statistical meth- ods such as hospital- and time-fixed effects were used to control for other potentially con- founding factors.

Analytic model and data analysis

To isolate the effect of nurse staffing on pa- tient falls, we used a negative binomial model to investigate whether comprehensive nurse staffing characteristics affected the likelihood of patient falls. The following equation (1) presents the details as

Yuhym = F (Nurse Staffinguhym, Unit Covariatesuhym, Hh, Yeary,

Monthm, εuhym),

where the subscripts u, h, y, and m represent nursing unit, hospital, year, and month. Y rep- resents monthly patient falls. After assessing the distribution of monthly patient falls, we used a count model. So, F(·) represents a neg- ative binomial distribution function.

Nurse staffing characteristics included the key predictor variables: RN, LPN, and UAP care hours per patient day; skill mix; RN turnover; and temporary RN care hours per patient day. With the exception of temporary RN care hours per patient day, all other nurse staffing variables were continuous. For tempo- rary RN care hours per patient day, 2 dummy variables (moderate, high) were created; units

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Analysis of Nurse Staffing and Patient Outcomes 321

without any temporary RN use (low) served as a reference group. Unit covariates were those mentioned earlier. Hospital-fixed ef- fects (H) were also included to eliminate bias from unobserved hospital-level confounding factors that do not change over time, such as general hospital characteristics. We also in- cluded 2 time-fixed effects, year and month, and thereby controlled for fixed time effects that do not vary across units, such as the pro- motion of nationwide awareness of quality of care that are not observed empirically.

Similarly, to isolate the effect of comprehen- sive nurse staffing characteristics on quarterly falls with injuries, total pressure ulcers, and unit-acquired pressure ulcers, the same model in the equation (1) was estimated for quarterly falls with injuries, quarterly total pressure ul- cers, and quarterly unit-acquired pressure ul- cers. On the basis of assessment of the dis- tribution of these patient outcome variables, for injury falls and unit-acquired pressure ul- cers, Y represents binary outcomes, and F(·) thus represents a cumulative logit distribu- tion function. For the total pressure ulcers, F(·) represents a negative binomial distribu- tion function. To make correct statistical in- ferences, standard errors were adjusted for unit clustering.

To summarize, we used 2 analytic models (negative binomial and logit models) depend- ing on the distribution of the outcome vari- ables. Using these analytic models, we can estimate the relationship between compre- hensive nurse staffing characteristics and the likelihood of patient outcomes. In addition to controlling for unit characteristics using unit covariates, we also controlled for unobserved hospital characteristics and the time trend, which might affect patient outcomes by the analytic methods to reduce omitted-variable bias and to draw rigorous study findings. All the analyses were performed in STATA, ver- sion 10.0 (Stata Corp, College Station, Texas).

RESULTS

The Supplemental Digital Content Table (available at http://links.lww.com/JNCQ/

A73) presents descriptive statistics for the study variables. The average monthly staffing levels were 8.23, 0.42, and 1.41 care hours per patient day for RNs, LPNs, and UAPs, re- spectively. The average quarterly staffing lev- els were similar. In the case of LPN care hours per patient day, we found that about 45% of the sample units used zero LPN care hours. The average professional staff mix (ie, RNs/ [RNs + LPNs + UAPs] × 100) both monthly and quarterly was around 79.50%. The RN monthly turnover rate was 1.82%, whereas the RN quarterly turnover rate was 5.00%. Av- erage temporary RN care hours per patient day were 0.08 both monthly and quarterly. About 74% of nursing units did not use tem- porary RN staff in any month. The other 17% used more than zero and less than 0.3 care hour per patient day provided by temporary RN staff. Temporary RN staff provided equal to or greater than 0.3 care hour per patient day in another 9% of nursing units. When calcu- lated per quarter, 64% of nursing units did not use any temporary RN staff, 26% used more than zero and less than 0.3 care hour per pa- tient day, and 10% used equal to or greater than 0.3 care hour per patient day.

Table 1 presents the associations between (1) monthly patient falls and quarterly falls with injuries and (2) comprehensive nurse staffing characteristics. The first panel of Table 1 presents the impact of comprehen- sive nurse staffing characteristics on monthly patient falls. Two staffing characteristics were significantly related to the occurrence of pa- tient falls. With all other variables held con- stant, an hour increase in LPN care hours per patient day led to a decrease in patient falls by a factor of 0.540. In other words, when all other conditions are same, an increase of LPN care hours was related to a decrease in patient falls. Compared with nursing units without any temporary RN staff, units that used tem- porary RN staff to provide equal to or more than 0.3 care hour per patient day had a rate 1.552 times greater for patient falls, which means that nursing units using the higher lev- els of care hours of temporary RNs experi- enced greater occurrence of patient falls.

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Table 1. Associations of Patient Falls and Injury Falls With Nurse Staffing Characteristics

Monthly Patient Falls Quarterly Injury Falls

Negative Binomial Regression

Logit Regression

Nurse Staffing Characteristics IRR (SE) OR (SE)

Staffing levels RN nursing hours per patient day 1.060 (0.079) 1.330 (0.322) LPN nursing hours per patient day 0.540 (0.150)a 0.058 (0.115) UAP nursing hours per patient day 0.720 (0.156) 0.178 (0.200)

Professional staff mix Skill mix 0.956 (0.023) 0.820 (0.118)

Turnover RN turnover rate 1.015 (0.008) 0.996 (0.034)

Temporary nursing staff RN contract nursing care hours per

patient day No RN contract care hours

(reference group) 0 < RN contract care hours < 0.3 1.099 (0.162) 4.169 (2.684)a

RN contract care hours ≥ 0.3 1.552 (0.260)b 4.679 (4.907) N 470 158

Abbreviations: IRR, incident rate ratio; LPN, licensed practical nurse; OR, odds ratio; RN, registered nurse; UAP, unlicensed assistive personnel. All models controlled for unit size, unit type, dedicated education units and transforming care at the bedside units status and included hospital fixed-effects and time (year and either month or quarter) fixed-effects. Standard errors (SE) are reported in parentheses, and are adjusted for clustering at the nursing unit level. aP < .05. bP < .01.

The second panel in Table 1 presents the impact of the comprehensive nurse staffing characteristics on quarterly falls with injuries. Only temporary RN staff use was significantly related to the occurrence of falls with injuries. Compared with nursing units without any use of temporary RN staff, units that used greater than zero but less than 0.3 care hour per pa- tient day provided by temporary RN staff had a rate 4.169 times greater for injury-related falls. Table 2 presents the associations between (1) comprehensive nurse staffing character- istics and (2) quarterly pressure ulcers and quarterly unit-acquired pressure ulcers. None of the staffing characteristics were signifi- cantly related to the occurrences of pressure ulcers.

DISCUSSION

In this study, with all other conditions held constant, greater use of LPNs was related to a decrease in patient falls, and increased use of temporary RN staff was related to in- creased patient falls and falls with injuries. Given the Centers for Medicare and Medicaid Services’ decision not to reimburse for cer- tain preventable adverse outcomes such as patient falls,34 the present findings provide valuable evidence regarding the linkages be- tween nurse staffing and patient outcomes. Using comprehensive characteristics of nurse staffing and a longitudinal methodology pro- vide a more definitive test of the relation- ships between staffing and outcomes than that

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Analysis of Nurse Staffing and Patient Outcomes 323

Table 2. Associations of Pressure Ulcer and Unit-Acquired Pressure Ulcer With Nurse Staffing Characteristics

Quarterly Pressure Ulcer

Quarterly Unit Acquired Pressure

Ulcer

Negative Binomial Regression

Logit Regression

Nurse Staffing Characteristics IRR (SE) OR (SE)

Staffing levels RN nursing hours per patient day 0.946 (0.090) 0.837 (0.127) LPN nursing hours per patient day 1.287 (0.608) 1.900 (1.290) UAP nursing hours per patient day 0.792 (0.244) 0.665 (0.392)

Professional staff mix Skill mix 1.016 (0.036) 1.003 (0.047)

Turnover RN turnover rate 0.998 (0.011) 1.038 (0.028)

Temporary nursing staff RN contract nursing care hours per

patient day No RN contract care hours

(reference group) 0 < RN contract care hours <0.3 0.847 (0.126) 0.564 (0.286) RN contract care hours ≥0.3 0.928 (0.304) 0.623 (0.378)

N 161 160

Abbreviations: IRR, incident rate ratio; LPN, licensed practical nurse; OR, odds ratio; RN, registered nurse; UAP, unlicensed assistive personnel. All models controlled for unit size, unit type, dedicated education units and transforming care at the bedside units status and included hospital fixed-effects and time (year and quarter) fixed effects. Standard errors (SE) are reported in parentheses, and are adjusted for clustering at the nursing unit level.

offered by earlier studies and may account for the robust associations identified between the comprehensive staffing characteristics and pa- tient quality indicators found here.

The US Department of Health and Human services found a strong association between nurse staffing levels and quality of patient care by using data from more than 4000 hospitals.35 Those nursing-sensitive outcomes included urinary tract infections, pressure ul- cers, hospital-acquired pneumonia, and deep vein thrombosis. The present findings add to the evidence of this relationship between nurse staffing and quality of patient care.

Our most important finding is that in- creased levels of temporary RN staffing re-

sulted in greater patient falls—both non– injury-related and injury-related falls. This is consistent with findings of previous studies,23,36 and it suggests that the use of temporary RN staff may be detrimental to the quality of patient care. Given the present study’s limitations, one should be cautious in interpreting its results. As mentioned earlier, 74% of unit-month data points and 64% of unit-quarter data points were zero temporary RN care hours per patient day. About 9% to 10% of sample reported equal to or greater than 0.3 temporary RN hours. That means in this study sample, relatively fewer nursing units used temporary RN staff. Although we found the statistically significant findings of

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324 JOURNAL OF NURSING CARE QUALITY/OCTOBER–DECEMBER 2014

relationships between use of temporary RN staff and patient falls, this may not have enough power to have clinical significance given small variations of temporary RN staffing variables with the study sample. How- ever, using the small sample, we found sta- tistically significant findings so that the re- lationship between temporary RN staff and patient falls may also be seen in a larger sample. Future research needs to investigate the levels of temporary RN staffing, which might be harmful to patient falls, with larger samples.

Another concern in interpreting the results is related to variables not accounted for in this study that might also affect the quality of patient care. Aiken and colleagues,29 after accounting for nurse staffing, RN education, and work environment, found that the asso- ciation between temporary RN staffing levels and quality of patient care was not significant. It is possible that unfavorable work environ- ments for nurses can lead to both increased use of temporary RN staff and poor quality of care. Using temporary RN staff can aggra- vate unfavorable work conditions. Either way, this reciprocal relationship between the use of temporary RN staff and unfavorable work conditions can have a negative effect on qual- ity of patient care.

Thus, one practical implication for qual- ity of care in this study is that nursing units should be aware that the use of temporary RN staff may have an impact on quality of patient care, and thus they should try to re- duce the use of temporary RN staff. If they have to use temporary RN staff, they should monitor their work environments to ensure the quality of patient care. Another implica- tion for quality of care is related to the reason behind the use of temporary RN staff. As men- tioned earlier, the main reasons for employing temporary RN staff are staff absences, recruit- ment, retention, and vacancies.22 One way to reduce the use of temporary nursing staff is to make staffing levels stable. Providing favor- able work conditions would help staffing lev- els remain stable, which ensures the quality of patient care.

The finding that adding more LPN care hours led to decreased levels of patient falls is in contrast with previous findings for patient outcomes. Glance and colleagues37 found that an increased ratio of LPNs to total nursing staff was related to an increase in mortality and sepsis in hospital patients. These contra- dictory findings might be due to the types of patient outcomes considered. Mortality and sepsis can be more complicated and require more care from RNs, whereas adding an LPN can lead to a decreased level of patient falls be- cause LPNs can conduct patient surveillance rounds and prevent such events. Another pos- sible explanation could be omitted variable biases. Although this study controlled nurs- ing unit covariates, patient characteristics and case mix were not controlled. Those omit- ted variables could relate to both levels of LPN staffing and patient outcomes. For fu- ture studies, it is important to understand the level at which we can use LPNs to provide pa- tient care to ensure quality of care (eg, hours per patient day or proportion of nursing care hours). Similar to the findings for temporary RN staff care hours, we need to consider that about 45% of the sample reported zero LPN care hour. Although the study findings were statistically significant, readers need to be cau- tious to interpret this as clinical significance.

Another practical implication of this study is that organizations should not focus solely on nurse staffing levels. This study used compre- hensive nurse staffing characteristics, includ- ing nurse staffing, skill mix, RN turnover, and temporary RN staff. Significant findings were identified for LPN staffing level and tempo- rary nursing staff use. This suggests that staff nurses and nurse managers should pay atten- tion to staff composition as well as staffing levels. To capture both staffing levels and staff composition, nurse managers can exam- ine the care provided by RN and LPN staff and number of hours or proportion of nursing care hours. It is also important to understand that nursing staff other than RNs, including LPNs and temporary RN staff, influence the qual- ity of patient care. In health care facilities, staffing standards should be established not

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Analysis of Nurse Staffing and Patient Outcomes 325

only for RNs but for LPNs and temporary nurs- ing staff as well. Currently, staffing strategies emphasize RN staffing due to State staffing policy (eg, mandating minimum nurse to pa- tient ratios, public reporting, having staffing committees).38 However, LPN staffing may help to prevent certain kinds of adverse pa- tient outcomes, such as patient falls. For those units with higher risk of patient falls, hiring more LPNs may be a cost-effective way to pre- vent patient falls at the same time to reduce health care costs related to falls. According to the Bureau of Labor Statistics,39 LPNs are $24 000 less expensive than RNs on average per year, and when used to supplement RNs rather than replace them, they may be effec- tive in reducing falls. Thus, health care facili- ties need to develop the staffing strategies us- ing such evidence to reduce cost and improve quality of patient care.

Regarding temporary RN staffing, re- searchers should investigate levels of tem- porary RN staffing in relation to quality. The present analyses did not suggest recom- mended levels because they are based on the sampling distribution of temporary nursing care hours. A replication with a larger sam- ple is needed to establish staffing standards.

Although the State of California has im- plemented mandatory nurse-to-patient ratios, these include no specific recommendation about temporary RN staff. Also, it is not yet known whether consistent use of tem- porary RN staff might be harmful to patient care in comparison with occasional use of temporary RN staff. The levels and fluctua- tion of temporary RN staff usage should be investigated.

This study has several limitations. The convenience sample used lacked population representativeness, and the findings are not applicable to hospitals in other regions. An- other potential limitation is that other miss- ing variables might affect patient quality of care. Although the study controlled for sev- eral time-invariant nursing unit characteris- tics, it did not control for time-variant charac- teristics such as leadership change. Also, the study did not control for the unit case mix and individual patient characteristics such as age or comorbidity related to risk of falls and pressure ulcers, because these data were not available for all units. Further research is needed to account for confounding vari- ables that might affect the quality of patient care.

REFERENCES

1. Juraschek SP, Zhang X, Ranganathan V, Lin VW. United States registered nurse workforce report card and shortage forecase. Am J Med Qual. 2012;27(3):241-249.

2. Buerhaus PI, Auerbach DI, Staiger DO. The recent surge in nurse employment: causes and implications. Health Aff. 2009;28(4):w657-w668.

3. Bae SH, Brewer CS, Kovner CT. State mandatory over- time regulations and newly licensed nurses’ manda- tory and voluntary overtime and total work hours. Nurs Outlook. 2012;60(2):60-71.

4. Castle NG, Anderson RA. Caregiver staffing in nurs- ing homes and their influence on quality of care: us- ing dynamic panel estimation methods. Med Care. 2011;49(6):545-552.

5. Blegen MA, Vaughn T, Vojir CP. Nurse staffing lev- els: impact of organizational characteristics and regis- tered nurse supply. Health Serv Res. 2008;43(1, pt 1): 154-173.

6. Aiken LH, Cimiotti JP, Sloane DM, Smith HL, Flynn L, Neff DF. Effects of nurse staffing and nurse education on patient deaths in hospitals with different nurse work environments. Med Care. 2011;49(12):1047- 1053.

7. Kane RL, Shamliyan T, Mueller C, Duval S, Wilt TJ. Nurse Staffing and Quality of Patient Care. Rockville, MD: Agency for Healthcare Research and Quality; 2007.

8. Kalisch BJ, Tschannen D, Lee KH. Missed nursing care, staffing, and patient falls. J Nurs Care Qual. 2012;27(1):6-12.

9. Staggs VS, Knight JE, Dunton N. Understanding unassisted falls: effects of nurse staffing level and nursing staff characteristics. J Nurs Care Qual. 2012;27(3):194-199.

10. Tai TW, Bame SI, Robinson CD. Review of nurs- ing turnover research, 1977-1996. Soc Sci Med. 1998;47(12):1905-1924.

Copyright © 2014 Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited.

LWW/JNCQ JNCQ-D-13-00147 July 28, 2014 16:24

326 JOURNAL OF NURSING CARE QUALITY/OCTOBER–DECEMBER 2014

11. Price JL, Mueller CW. A causal model of turnover for nurses. Acad Manage J. 1981;24(3):543-565.

12. Price JL. The Study of Turnover. Ames, IA: Iowa State University Press; 1977.

13. Cavanagh SJ. Nursing turnover: literature review and methodological critique. J Adv Nurs. 1989;14(7):587- 596.

14. Staw BM. The consequences of turnover. J Occup Behav. 1980;1(4):253-273.

15. Bae SH, Mark B, Fried B. Impact of nursing unit turnover on patient outcomes in hospitals. J Nurs Scholarsh. 2010;42(1):40-49.

16. Castle NG, Engberg J. Staff turnover and quality of care in nursing homes. Med Care. 2005;43(6):616- 626.

17. Castle NG, Engberg J. The influence of staffing char- acteristics on quality of care in nursing homes. Health Serv Res. 2007;42(5):1822-1847.

18. O’Brien-Pallas L, Murphy GT, Shamian J, Li X, Hayes LJ. Impact and determinants of nurse turnover: a pan- Canadian study. J Nurs Manage. 2010;18(8):1073- 1086.

19. Dalton DR, Todor WD. Turnover turned over: an ex- panded and positive perspective. Acad Manage Rev. 1979;4(2):225-235.

20. Pfeffer J. Some consequences of organizational de- mography: potential impacts of an aging work force on formal organizations. Research paper presented at: the meeting of the Committee on Aging, National Research Council, National Academy of Sciences; March 1979; Annapolis, MD.

21. Castle NG, Engberg J, Men A. Nursing home staff turnover: impact on nursing home compare quality measures. Gerontologist. 2007;47(5):650-661.

22. Hurst K, Smith A. Temporary nursing staff—cost and quality issues. J Adv Nurs. 2011;67(2):287-296.

23. Bae SH, Mark B, Fried B. Use of temporary nurses and nurse and patient safety outcomes in acute care hospi- tal units. Health Care Manage Rev. 2010;35(4):333- 344.

24. Castle NG. Use of agency staff in nursing homes. Res Gerontol Nurs. 2009;2(3):192-201.

25. Alonso-Echanove J, Edwards JR, Richards MJ, et al. Effect of nurse staffing and antimicrobial-impregnated central venous catheters on the risk for bloodstream infections in intensive care units. Infect Control Hosp Epidemiol. 2003;24(12):916-925.

26. Aiken LH, Sloane DM, Klocinski JL. Hospital nurses’ occupational exposure to blood: prospective, ret- rospective, and institutional reports. Am J Public Health. 1997;87(1):103-107.

27. Roseman C, Booker JM. Workload and environmen- tal factors in hospital medication errors. Nurs Res. 1995;44(4):226-230.

28. Aiken LH, Xue Y, Clarke SP, Sloane DM. Supplemental nurse staffing in hospitals and quality of care. J Nurs Adm. 2007;37(7-8):335-342.

29. Aiken LH, Shang J, Xue Y, Sloane DM. Hospital use of agency-employed supplemental nurses and patient mortality and failure to rescue. Health Serv Res. 2013;48(3):931-948.

30. Xue Y, Aiken LH, Freund DA, Noyes K. Quality out- comes of hospital supplemental nurse staffing. J Nurs Adm. 2012;42(12):580-585.

31. American Nurses Association. ANA Indicator His- tory. Silver Spring, MD: American Nurses Association; 1999.

32. National Quality Forum. National Voluntary Consen- sus Standards for Nursing-Sensitive Care: An Initial Performance Measure Set. Washington, DC: National Quality Forum; 2004.

33. American Nurses Association. The National Database Web site. http://www.nursingworld.org/MainMenu Categories/ThePracticeofProfessionalNursing/Patient SafetyQuality/Research-Measurement/The-National- Database.aspx. Updated 2013. Accessed October 1, 2013.

34. Clancy CM. CMS’s hospital-acquired condition lists link hospital payment, patient safety. Am J Med Qual. 2009;24(2):166-168

35. Needleman J, Buerhaus P, Mattke S, Stewart M, Zelevinsky K. Nurse-staffing levels and the quality of care in hospitals. New Eng J Med. 2002;346(22):1715- 1722.

36. North N, Leung W, Ashton T, Rasmussen E, Hughes F, Finlayson M. Nurse turnover in New Zealand: costs and relationships with staffing practises and patient outcomes. J Nurs Manage. 2013;21(3): 419-428.

37. Glance LG, Dick AW, Osler TM, Mukamel DB, Li Y, Stone PW. The association between nurse staffing and hospital outcomes in injured patients. BMC Health Serv Res. 2012;12:247.

38. American Nurses Association. Nurse staffing plans & ratios. http://www.nursingworld.org/MainMenu Categories/Policy-Advocacy/State/Legislative-Agenda -Reports/State-StaffingPlansRatios. Updated 2014. Accessed January 2, 2014.

39. Bureau of Labor Statistics, United States Department of Labor. Occupational outlook handbook. http:// www.bls.gov/ooh/Healthcare. Published March 29, 2012. Accessed January 2, 2014.

Copyright © 2014 Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited.http://www.nursingworld.org/MainMenuCategories/ThePracticeofProfessionalNursing/PatientSafetyQuality/Research-Measurement/The-National-Database.aspxhttp://www.nursingworld.org/MainMenuCategories/ThePracticeofProfessionalNursing/PatientSafetyQuality/Research-Measurement/The-National-Database.aspxhttp://www.nursingworld.org/MainMenuCategories/ThePracticeofProfessionalNursing/PatientSafetyQuality/Research-Measurement/The-National-Database.aspxhttp://www.nursingworld.org/MainMenuCategories/ThePracticeofProfessionalNursing/PatientSafetyQuality/Research-Measurement/The-National-Database.aspxhttp://www.nursingworld.org/MainMenuCategories/Policy-Advocacy/State/Legislative-Agenda-Reports/State-StaffingPlansRatioshttp://www.nursingworld.org/MainMenuCategories/Policy-Advocacy/State/Legislative-Agenda-Reports/State-StaffingPlansRatioshttp://www.nursingworld.org/MainMenuCategories/Policy-Advocacy/State/Legislative-Agenda-Reports/State-StaffingPlansRatioshttp://www.bls.gov/ooh/Healthcarehttp://www.bls.gov/ooh/Healthcare

 
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Analyzing Data In A Quantitative Study

Introduction

Quantitative research design provides an approach to finding scholarly evidence.  There are a variety of philosophical considerations, strategies of inquiry, and methods of data collection and analysis based on the study question and the types and numbers of variables.  For example, having one or more dependent and/or independent variables is what prescribes the statistical tests needed to answer the study question(s).  It is important for nurse researchers, leaders, educators, and practitioners to know how to select the correct statistical analysis for a study.

Upon successful completion of this assignment you should be able to:

  • Select a data analysis method / tests appropriate for a potential research study.
  • Expound on interpretation of data for a quantitative study.

Resources

Instructions

  1. Read chapters 7 and 8 in Research Design: Qualitative, Quantitative, and Mixed Method Approaches (2018),and chapters 4 and 8 in Practical Research: Planning and Design (2016). Review all other materials listed.
  2. Navigate to the threaded discussion below and respond to the following:
    1. Post your quantitative question.
    2. Describe your proposed data collection tool.
    3. Respond to the questions found in Practical Research: Planning and Design (2016) pages 245-246 and post your responses.  For your convenience, the checklist is included in the resources above.
    4. Use Dr. Finger’s Chart of Statistical Tests and your texts from GNUR-528 Biostatistics and Epidemiology course to determine what statistical tests you would select to demonstrate the answer(s) to your problem, subproblems, and research question.  Be sure and refer to the studies related to your topic found in OCLS.  Post at least one test to use on your data along with your rationale.
    5. What interpretive criteria would you use to give meaning and significance to your findings?
    6. What if your findings do not support your hypothesis or hunch?
    7. This discussion should be referenced with at least three references.
  3. Your initial post is due by day five of the workshop.
  4. The post should be written in scholarly and scientific writing with use of APA style.
  5. Read and respond to at least two of your classmates’ initial postings and any questions you are asked in your initial post by the end of the workshop.

Navigate to the threaded discussion here.

Assessment Criteria

Criteria

16 Points

12 Points

8 Points

4 Points

Quality

Your postings are well developed and answers provide clear evidence of critical thinking.

Your questions or observations add greater depth to the discussion by introducing new ideas.

A current, professional source is used to validate your thoughts.

Your postings show some development and some critical thinking is evident in your answers.

Your questions and observations add to the discussion by expanding the ideas of others.

A current, professional source is used to validate your thoughts.

Your postings show nominal development and only the beginnings of critical thinking.

Your contributions (questions or observations) do not clearly add to the discussion.

No source is used.

Your postings show no development and are mostly a reiteration of what the textbook or others have said.

Your questions and observations detract from the discussion.

No source is used.

Criteria

12 points

8 Points

4 Points

0 Points

Timeliness

Your initial posting to the question or topic assigned in the workshop activity is made by day five of the workshop.

Your initial posting to the question or topic assigned in the workshop activity is made by the day six of the workshop.

Your initial posting to the question or topic assigned in the workshop activity is made by day seven of the workshop.

No initial post made.

Criteria

12 Points

8 Points

4 Points

0 Points

Interaction

You respond to a minimum of two other classmates as well as all follow-up faculty questions directed to you. 

You are clearly collaborative by taking the initiative to respond to classmates’ questions, providing clarification and insight on issues in the discussion. 

You respond to two classmates and some of the faculty follow-up questions directed to you. 

You are collaborative in some situations and show some initiative in workshop discussions.

You respond to two classmates but do not respond to faculty follow-up questions directed to you. 

You show little initiative in discussions and your presence is not collaborative.

You do not respond to the postings of others in the discussion. 

Total Points

 
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Construction Law

NewSchool of Architecture + DesignSpring 2017 – Course Syllabus

CM 354 Construction Law Name:

Extra Credit Assignment #1 (Worth an extra homework assignment)

Due 6/4 FIRST OF CLASS

NOTE: It will NOT be accepted after this date

A school hires a contractor to do some remodeling work at the school. Because of the risk of injury to students the school decides to have the contractor perform the work during the summer when the school is shut down. The contract requires:

1. The contractor to remodel the first floor including relocating the restrooms and relocating the underground sewer.

2. The contractor to carry $5 million in insurance

3. The schedule for the project is for 90 calendar days.

4. The cost to perform the work as set at $350,000.

The architect was hired to prepare the plans and to provide project oversight on behalf of the school district including responsibility to visit the site periodically to inspect the work.

The contractor, during the first 10 days had excavated the trenching for the sewer line. The architect had just visited the site to inspect the work and found the work being performed as the contract requires including the proper safety protection. However it also became clear that the contractor was falling behind on his schedule. In an effort to accelerate the schedule the contractor began working Saturdays to catch up.

It was the contractor’s superintendent’s usual practice that he install a barricade around the excavated sewer trench as the bottom of the trench was 6-feet below the surface. Because they had started working six days a week to catch up, this particular Saturday the superintendent did not reinstall the barricade at the end of their shift at 3:30 so they can get a quick start on Monday. He did lock the door before he left.

However that Saturday, at 5:00 the principal of the school wanted to show one of the teachers the work that was being done. He unlocked the door and entered the large room. The space was dark as the permanent power had been shut off for safety of the contractor who was using temporary power for his own lighting and power. The principal, in an effort to find the temporary switch, stepped into the trench and broke several bones. To recover his medical payments he sued the contractor and architect for keeping an unsafe condition.

Discuss this case. Describe the responsibility of each party; contractor, architect and principal. What / whose insurances will play a role? Do you think the principal will collect?

Worth the potential of 20 points based on:

1. Thoroughness of answer

2. Completeness of answer

3. Reasonable conclusion based on legal principles

NOTE: A weak answer will score no points.

1

2

 
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inflammatory bowel disease (IBD) is a term for chronic inflammation of the bowel that includes ulcerative colitis and Crohn disease.

Inflammatory Bowel Disease

            Inflammatory bowel disease (IBD) is a term for chronic inflammation of the bowel that includes ulcerative colitis and Crohn disease. Possible causes and risks for IBD are gene susceptibility, environmental, epithelial cell barrier function alteration, and altered immune response to intestinal microflora (Huether & McCance, 2017). The mucosal epithelium loses its ability to discern normal intestinal antigens from harmful ones and cell-mediated immunity is activated. Dendritic cells are activated, T cells differentiate, and proinflammatory cytokines and chemokines are produced (Huether & McCance, 2017). The result of the altered immune response is chronic inflammation (Centers for Disease Control and Prevention, 2018; Huether & McCance, 2017). Ulcerative colitis and Crohn disease are slightly different with location and cellular appearance. With ulcerative colitis, the cellular inflammation and destruction can lead to frequent bowel movements, pain, fever, bloody stools, fissures, and abscess. Those with Crohn disease may experience diarrhea, pain, fistulae, and obstruction (Huether & McCance, 2017).

            According to the Crohn’s and Colitis Foundation of America (2014), the onset of IBD can occur at any age, but is most common between the ages of 15 and 35. When it comes to age, Herzog et al. (2018) found that disease onset results in no change of IBD behavior or progression. Similarly, a metanalysis found that age of diagnosis does not impact mortality (Duricova, Burisch, Jess, Gower-Rousseau, & Lakatos, 2014). However, pediatric diagnosis of IBD is found to have higher rates of anemia, and stomatitis, and lower rates of arthralgia and osteopenia (Herzog et al., 2018).

Psoriasis

            Psoriasis is a chronic and relapsing condition of the skin, scalp, and nails. Psoriasis appears to be T cell driven. Dendritic cells react to a trigger and secrete cytokines (Fischer, 2017). Interleukins are secreted, impacting keratinocyte proliferation, cytokine secretion, and more activation of T cells (Fischer, 2017). Psoriasis is marked by a thickening of the dermis and epidermis because of cellular hyperproliferation, altered keratinocyte differentiation, and expanded dermal vasculature, causing scales and thickened red plaques (Huether & McCance, 2017). Psoriasis can occur at any age, although generally happens by the age of 35. There is not a lot of information on the factor of age. Gulliver, Parfre, Gulliver, Randell, and Connors (2016) state that psoriasis is associated with excess cardiovascular-related deaths and decreased longevity of 20 years. The authors state there are no predictive factors for at risk patients (Gulliver et al., 2016).

Comparison of IBD and Psoriasis

            IBD and psoriasis seem to be the result of altered innate and cell-mediated response. Both have a cellular-mediated immune response that result in a chronic inflammatory response. In both conditions, dendritic cells are activated, T cells are mobilized, and eventually inflammatory mediators are released. Patients who suffer experience both periods of remission and exacerbation or flares. However, their locations and clinical manifestations are very different. Psoriasis causes the over-proliferation of the dermis and epidermis. IBD is marked by damage and inflammation to the mucosa and submucosa.

References

Centers for Disease Control and Prevention. (2018). What is inflammatory bowel disease (IBD)?

Retrieved from https://www.cdc.gov/ibd/what-is-IBD.htm

Crohn’s and Colitis Foundation of America (2014). The facts about inflammatory bowel

diseases. Retrieved from https://www.crohnscolitisfoundation.org/assets/pdfs/updatedibdfactbook.pdf

Duricova, D., Burisch, J., Jess, T., Gower-Rousseau, G., & Lakatos, P. (2014). Age-related

            differences in presentation and course of inflammatory bowel disease: An update on the

            population-based literature. Journal of Crohn’s and Colitis, 8(11), 1351-1361. doi:

https://doi.org/10.1016/j.crohns.2014.05.006

Fischer, S. (2017). 2017 update: Etiology and pathogenesis of psoriasis. Retrieved from

https://www.medpagetoday.com/resource-centers/ra-pso-psa-related-disorders/2017-update-etiology-and-pathogenesis-psoriasis-/1301

Gulliver, W., Parfre, B., Gulliver, S., Randell, S., & Connors, S. (2016). Early age of onset of

            psoriasis (<25 years of age) may be a predictor for cardiovascular disease in patients with

            severe psoriasis. Journal of the American Academy of Dermatology, 74(5), AB244. doi:

https://doi.org/10.1016/j.jaad.2016.02.955

Herzog, D., Fournier, N., Buehr, P., Rueter, V., Koller, R., Helyand, K., Nydegger, A.,

Spalinger, J., Schibli, S., Petit, L., & Braegger, C. (2018). Age at disease onset of inflammatory bowel disease is associated with later extraintestinal manifestations and complications. European Journal of Gastroenterology & Hepatology, 30(6), 598-607. doi: 10.1097/MEG.0000000000001072

Huether, S.E., & McCance, K.L. (2017). Understanding pathophysiology (6th ed.). St. Louis,

            MO: Mosby. 

REPLY  QUOTE EMAIL AUTHOR

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Emerging Areas Of Human Health

Topic: Health Issues for the Aging

As of 2014 health care expenditures in the United States are near 17% of our gross domestic product (GDP), with a major portion of Medicare funding goes towards chronic illness and care at the last 6 months of life. The Patient Protection and Affordable Care Act has made some initial legislative changes in our health system, but not sufficient to address our growing expenditures and caring for our large aging population. In this assignment, learners will synthesize issues in aging with health policy solutions by writing a paper on one health issue for older individuals addressed in the topic and offering a policy solution. Example of issue: In 2014, over 50% of the costs of institutional long-term care for older persons are paid for with public funds from Medicaid.

General Guidelines:

Use the following information to ensure successful completion of the assignment:

· Doctoral learners are required to use APA style for their writing assignments. 

· This assignment requires that at least three additional scholarly research sources related to this topic, and at least one in-text citation from each source be included.

· You are required to submit this assignment to LopesWrite. Please refer to the directions in the Student Success Center.

Directions:

Write a 1,000-1,250 word paper that addresses a health issue for older individuals. Include the following:

1. Evaluate what the literature suggests as a resolution to your chosen issue.

2. Discuss any attempts to incorporate the solution into public policy.

3. Determine the barriers to implementation of the solution.

4. Analyze the options being discussed for public and/or private funding.

5. Propose your own recommendation.

You are required to complete your assignment using real-world application. Real-world application requires the use of evidence-based data, contemporary theories, and concepts presented in the course. The culmination of your assignment must present a viable application in a current practice setting. 

 
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Life Stage Focus: Possible Alterations In Mental Health

Answer each question in a paragraph of 4-6 sentences. Include one APA citation per question to support your answers.

  1. Describe the developmental tasks of one age group, chosen from childhood, adolescence, young adulthood, or middle adulthood.
  2. Describe three possible alterations in mental health found in that stage of life.
  3. Discuss five effective nursing interventions for one of the mental health conditions you described. Include one CAM therapy and one therapeutic communication intervention.
  4. What positive outcomes can be anticipated from these interventions?
 
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Advanced Pathophysiology;Influencing Factors

NURS 6501: Advanced Pathophysiology

Arthritis

Lorie Valentin RN, BSN

Arthritis

            Osteoarthritis (OA) and Rheumatoid Arthritis (RA) are both diseases of the joints. Each is characterized by pain, swelling and stiffening of joints throughout the body (Huether & McCance, 2017). The most common joints affected are the hands, knees, hips and spine (Huether & McCance, 2017). In OA the breakdown of cartilage within the joints causes causing damage to the underlying bone and tissue. This breakdown causes a disruption of the fluid distribution mechanism within the joints allowing to much fluid into the cartilage, which in turn causes swelling in the joint and a weakening of the cartilage. As the cartilage weakens, breakdown occurs and causes further damage to the underlying boney structures, which leads to pain, inflammation and deformity of the joints. The most common cause of OA is repeated compression of the joints due to repetitive motion or constant pressure such as weight on the knees. In RA the causative factors are related to the increase of the synovial membrane comprised of pro-inflammatory cytokines (Hammer & McPhee, 2019). Where this increased lining comes in contact with out tissues such as cartilage and bone, it causes breakdown of those tissues.

Influencing Factors

            Though the rates for developing the disease are relatively equal in all parts of the world women are 30 percent more likely to develop RA than men (Hammer & McPhee, 2019). However, though the incidence rates are relatively equal between men and women, as they age women are typically more profoundly affected by OA (Huether & McCance, 2017). Ethnicity does not appear to play a major role in either disorder as it strikes individuals equally in different areas of the world (Hammer & McPhee, 2019).

Diagnosis and Treatment

            The diagnosis for OA is best achieved through thorough examination, in depth history, and radiological imaging to look for joint deformities (Huether & McCance, 2017).  The treatment for OA is based on the severity of the deterioration of the adjacent bone tissue in the joint. For mild to moderate disease physical therapy and exercise along with anti-inflammatory medications can improve mobility and pain. By improving muscle tone and flexibility many of the symptoms can be relieved. Possible addition of supplements and changes in diet can help decrease the inflammation characteristic of OA. More aggressive treatment for progressive disease might include steroid injections or surgery to replace the joint.

            The diagnosis for RA is much more complicated and is reliant on physical assessment, history and presentation. The most significant finding during evaluation that would point to RA is the swelling of the joints. Treatment should be immediate and aggressive to reduce the deterioration of the joint and the potential for damage to other organs within the body (Hammer & McPhee, 2019). Initial treatment for RA should be started with disease-modifying antirheumatic drugs (DMARDs), such as methotrexate, sulfasalazine, or leflunomide (Huether & McCance, 2017). Like OA, RA treatment should also include physical and occupational therapy to improve muscle tone and flexibility as well as anti-inflammatory medications such as NSAIDS and steroids.

References

Hammer, G. D., & McPhee, S. J. (2019). Pathophysiology of disease: An introduction to clinical

medicine (8th ed.). New York, NY: McGraw-Hill Education

Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology (6th ed.). St. Louis,

MO: Mosby

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Analyzing Data In A Quantitative Study

Introduction

Quantitative research design provides an approach to finding scholarly evidence.  There are a variety of philosophical considerations, strategies of inquiry, and methods of data collection and analysis based on the study question and the types and numbers of variables.  For example, having one or more dependent and/or independent variables is what prescribes the statistical tests needed to answer the study question(s).  It is important for nurse researchers, leaders, educators, and practitioners to know how to select the correct statistical analysis for a study.

Upon successful completion of this assignment you should be able to:

  • Select a data analysis method / tests appropriate for a potential research study.
  • Expound on interpretation of data for a quantitative study.

Resources

 
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Post- David;Share insights on how the factor you selected impacts the pathophysiology of the immune disorder your colleague selected.

Respond on to  two different days who selected different immune disorders and/or factors than you, in the following ways:

Share insights on how the factor you selected impacts the pathophysiology of the immune disorder your colleague selected.

Expand on your colleague’s posting by providing additional insights or contrasting perspectives based on readings and evidence.

                                                    Main Post

                            Irritable Bowel Syndrome (IBS):

Irritable bowel syndrome is a problem of a bowel function of the gastrointestinal tract.  IBS is one of the most common reasons for gastroenterologist consultation (Hammer & McPhee, 2019).  Irritable bowel syndrome symptoms are persistent abdominal pain, gas, bloating and with bowel disturbance; there are four subtypes of IBS: constipation (IBS-C), diarrhea (IBS-D), mixed (IBS-M), or unsubtyped IBS (IBS-U) (Kosako et al., 2018).  The incidence of IBS is higher in women; it is 1.5 to 3 times higher than men; with greater incidence in youth and middle age (Huether & McCance, 2017).

There is no known pathophysiology of irritable bowel syndrome and no specific biomarker for the disease (Huether & McCance, 2017).  Increasing evidence showed due to the different types of symptoms presentation of IBS that there are possibilities of correlation to altered gut microflora, gut immune responses, neuroendocrine cell function, the brain-gut axis, genetic predisposition and epigenetic factor (Huether & McCance, 2017). Despite the global frequency and disease burden of IBS, its underlying pathophysiology remains unclear (Ng QX et al., 2018).  Inflammation may provide a pathogenic role in IBS; research has shown the occurrence of mucosal irritation at the microscopic and molecular degree in IBS (Ng QX et al., 2018).  It also been reported that considerable overlaps between IBS and inflammatory bowel disease (Ng QX, et al., 2018). 

Psoriasis:

Psoriasis is one of the common issues of chronic skin inflammation. The prevalence of psoriasis affects both sexes and in most ethnic groups (Huether & McCance, 2017).  Most common occurrences are in people in their 30s, but it can also happen soon after birth (Hammer & McPhee, 2019).  Familial history of psoriasis is common, and the genetic process is complicated (Huether & McCance, 2017). 

The inflammatory dynamic of psoriasis involves the multifaceted interaction between macrophages, fibroblasts, dendritic cells, natural killer cells, T helper cells, and regulatory T cells. The influence of these immune cells can signal the secretion of multiple inflammatory mediators such as interferon, tumor necrosis factor-alpha, and various cytokines including interleukin 12, 23 and 17 (Huether & McCance, 2017).  

Maladaptive consequences of IBS and psoriasis:

Skin diseases, including psoriasis, appeared to impact a substantial adverse effect on patients’ health-related quality of life (Jung et al., 2018).  Individuals with psoriasis report that the illness has various physical and mental implications, such as social isolation and stress, depression, shame, and anxiety (Jung et al., 2018).

Patients with irritable bowel syndrome (IBS) have been found to have a significant reduction in quality of life (Arluwaili, et al., 2018). People with IBS report that the disease broth substantial psychosocial consequences such as social lifestyle and activities, emotional, food, and diet interest (Arluwaili, et al., 2018).

Refences

Alruwaili, A. M. M., Albalawi, K. S. A., Alfuhigi, F. R. D., Alruwaili, A. F., Altaleb, B. A. A., & Aljarid, J. S. (2018). Effects of Irritable Bowel Syndrome (IBS) on the health-related quality of Life among Saudi Males at Al-Jouf, Kingdom of Saudi Arabia. Egyptian Journal of Hospital Medicine73(4), 6581–6585. Retrieved from https://search-ebscohost-com.ezp.waldenulibrary.org/login.aspx?direct=true&db=a9h&AN=132302964&site=eds-live&scope=site

Hammer, G. D., & McPhee, S. J. (2019). Pathophysiology of disease: An introduction to clinical medicine (8th ed.). New York, NY: McGraw-Hill Education.

Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology (6th ed.). St. Louis, MO: Mosby.

Jung, S., Lee, S.-M., Suh, D., Shin, H. T., & Suh, D.-C. (2018). The association of socioeconomic and clinical characteristics with health-related quality of life in patients with psoriasis: a cross-sectional study. Health And Quality Of Life Outcomes16(1), 180. https://doi-org.ezp.waldenulibrary.org/10.1186/s12955-018-1007-7

Kosako, M., Akiho, H., Miwa, H., Kanazawa, M., & Fukudo, S. (2018). Impact of symptoms by gender and age in Japanese subjects with irritable bowel syndrome with constipation (IBS-C): A large population-based internet survey. BioPsychoSocial Medicine12. https://doi-org.ezp.waldenulibrary.org/10.1186/s13030-018-0131-2

Ng QX, Soh AYS, Loke W, Lim DY, & Yeo WS. (2018). The role of inflammation in irritable bowel syndrome (IBS). Journal of Inflammation Research, 345. Retrieved from https://search-ebscohost-com.ezp.waldenulibrary.org/login.aspx?direct=true&db=edsdoj&AN=edsdoj.4b6f79137ef348099ec9533069da7bbb&site=eds-live&scope=site

 
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